Hemax

(RECOMBINANT HUMAN ERYTHROPOIETIN)

 

Erythropoietin (EPO), sold under trade name Hemax, is a glycoprotein cytokine secreted by the kidney in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow. Low levels of EPO (around 10 mU/ml) are constantly secreted sufficient to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10,000 mU/ml) include any anemia, and hypoxemia due to chronic lung disease.

Erythropoietin is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and proximal convoluted tubule. It is also produced in perisinusoidal cells in the liver. Liver production predominates in the fetal and perinatal period; renal production predominates in adulthood.

Brand Drug Molecule Drug Form Packing Trade Rs. Retail Rs.
HEMAX [Epoetin:2000IU/0.5ml] Inj 1s          1,355          1,594
HEMAX [Epoetin:4000IU/0.4ml] Inj 1s          2,612          3,073
HEMAX [Epoetin:10000IU/ml] Inj 1s          3,825          4,500

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Neutromax

(Filgrastim 300μg)

 

Filgrastim, sold under the brand name Neutromax, is a medication used to treat low blood neutrophils due to a number of causes. This includes when it occurs following chemotherapy, radiation poisoning, HIV/AIDS, or is of unknown cause. It may also be used to increase white blood cells for gathering during leukapheresis.It is given either by injection into a vein or under the skin.

Common side effects include fever, cough, chest pain, joint pain, vomiting, and hair loss. Severe side effects include splenic rupture and allergic reactions. It is unclear if use in pregnancy is safe for the baby. Filgrastim is similar to naturally occurring granulocyte colony-stimulating factor (G-CSF).

Brand Drug Molecule Drug Form Packing Trade Rs. Retail Rs.
NEUTROMAX [Filgrastim:300mcg/ml] Inj 1s          3,600          4,000

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